NIH’s guidance, FAQs and resources thus far related to COVID-19

The NIH is deeply concerned for the health and safety of people involved in NIH research, and about the effects on the biomedical enterprise in the areas affected by the HHS declared public health emergency for COVID-19. Due to the potential exceptional impact, we want to assure our recipient community that NIH will be doing our part to help you continue your research.

This is a rapidly evolving situation and we will provide updated guidance and information as it becomes available.

See page update history.

Guidance

Overview

• Overview presentation (Powerpoint) – updated 4/6/2020
• Overview talking points (Word) – updated 4/6/2020

Proposal Submission & Award Management

• UPDATE: NIH Late Application Policy Due to Public Health Emergency for United States for 2019 Novel Coronavirus (COVID-19) – NOT-OD-20-091
• General Frequently Asked Questions (FAQs) – Proposal Submission and Award Management Related to COVID-19 – NOT-OD-20-083
• Flexibilities Available to Applicants and Recipients of Federal Financial Assistance Affected by COVID-19 – NOT-OD-20-086
• Guidance for Cost-Related Flexibilities Available to Support of Competitive Research (SCORE) Award Recipients Affected by COVID-19 – NOT-GM-20-026
• Contracts must be handled on a case by case basis. Details regarding any contract must be directed to the cognizant Contracting Officer. Salary changes must be handled by the contracting officer.

Human Subjects & Clinical Trials

• Guidance for NIH-funded Clinical Trials and Human Subjects Studies Affected by COVID-19 – NOT-OD-20-087
• FDA Guidance on Conduct of Clinical Trials of Medical Products during COVID-19 Pandemic 
• OHRP COVID-19 Resources
  • OHRP Guidance on COVID-19
  • Live Videocast on Tuesday, April 28 from 1-2pm ET

Animal Welfare

• COVID-19 Pandemic Contingency Planning for Animal Care and Use Programs
• Flexibilities for Assured Institutions for Activities of Institutional Animal Care and Use Committees (IACUCs) Due to COVID-19 – NOT-OD-20-088

Peer Review

• Coronavirus Update: Guidance for Peer Reviewers
• Based on NIH Guidance on Travel and Meetings , in-person NIH peer review meetings are being held in alternate formats. Scientific review officers will be in contact with peer reviewers about these changes.

FAQs – FAQs last updated on April 20, 2020 (history).

• NIH FAQs: COVID-19 Flexibilities for Applicants and Recipients

Funding

COVID-19 Funding and Funding Opportunities – Open Mike Blog 

Funding Opportunities Specific to COVID-19

Number	Title	Participating Organizations	Release Date
NOT-AA-20-011	Notice of Special Interest:  Availability of Administrative Supplements and Competitive Revision Supplements on Coronavirus Disease 2019 (COVID-19) within the Mission of NIAAA	National Institute on Alcohol Abuse and Alcoholism (NIAAA)	April 16, 2020
NOT-LM-20-010	Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements for Research on Coronavirus Disease 2019 (COVID-19)	National Library of Medicine (NLM)	April 16, 2020
NOT-NS-20-046	Notice of Special Interest regarding the Availability of Administrative Supplements and Urgent Competitive Revisions for the Establishment and Maintenance of a Research Database for Neurological Manifestations of the SARS-CoV-2	National Institute of Neurological Disorders and Stroke (NINDS)	April 14, 2020
NOT-OD-20-097	Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements and Urgent Competitive Revisions for Research on the 2019 Novel Coronavirus and the Behavioral and Social Sciences	Office of Behavioral and Social Sciences Research (OBSSR) National Heart, Lung, and Blood Institute (NHLBI) National Institute on Aging (NIA) National Institute on Alcohol Abuse and Alcoholism (NIAAA) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institute of Environmental Health Sciences (NIEHS) National Center for Complementary and Integrative Health (NCCIH) National Cancer Institute (NCI)	April 13, 2020
NOT-ES-20-020	Notice of Special Interest (NOSI): NIEHS Support for Understanding the Impact of Environmental Exposures on Coronavirus Disease 2019 (COVID-19)	National Institute of Environmental Health Sciences (NIEHS)	April 10, 2020
NOT-ES-20-019	Notice of Early Expiration of NOT-ES-20-015, “Notice of Special Interest (NOSI): NIEHS Support for Understanding the Impact of Environmental Exposures on Coronavirus Disease 2019 (COVID-19)	National Institute of Environmental Health Sciences (NIEHS)	April 10, 2020
NOT-ES-20-017	NIEHS Worker Training Program Coronavirus and Infectious Disease Response Training (Admin Supp Clinical Trial Not Allowed)	National Institute of Environmental Health Sciences (NIEHS)	April 10, 2020
NOT-ES-20-016	Notice of Early Expiration of “Notice of Special Interest (NOSI) regarding the NIEHS Worker Training Program Coronavirus and Infectious Disease Response Training (Admin Supp Clinical Trial Not Allowed)”	National Institute of Environmental Health Sciences (NIEHS)	April 10, 2020
NOT-EB-20-008	Notice of Special Interest (NOSI): Availability of Emergency Competitive Revision and Administrative Supplements on Biomedical Technologies for Coronavirus Disease 2019 (COVID-19)	National Institute of Biomedical Imaging and Bioengineering (NIBIB)	April 10, 2020
NOT-EB-20-007	Notice of Special Interest (NOSI): Development of Biomedical Technologies for Coronavirus Disease 2019 (COVID-19)	National Institute of Biomedical Imaging and Bioengineering (NIBIB)	April 10, 2020
NOT-EB-20-006	Notice of Special Interest (NOSI): Small Business Research and Development of Biomedical Technologies for Coronavirus Disease 2019 (COVID-19)	National Institute of Biomedical Imaging and Bioengineering (NIBIB)	April 10, 2020
NOT-GM-20-027	Notice of Special Interest (NOSI): Urgent Competitive Revisions to Accelerate Research on the Development of Predictive Models of the Spread of SARS-CoV-2 and Outcomes of Potential Public Health Interventions on COVID-19	National Institute of General Medical Sciences (NIGMS)	April 10, 2020
NOT-AT-20-011	Notice of Special Interest (NOSI): Availability of Administrative Supplements and Urgent Competitive Revisions for Research on Stress Management in Relation to Coronavirus Disease 2019 (COVID-19)	National Center for Complementary and Integrative Health (NCCIH) National Institute on Aging (NIA) National Institute on Alcohol Abuse and Alcoholism (NIAAA)	April 10, 2020
NOT-CA-20-042	Notice of Special Interest (NOSI): National Cancer Institute Announcement Regarding Availability of Urgent Competitive Revision and Administrative Supplements on Coronavirus Disease 2019 (COVID-19)	National Cancer Institute (NCI)	April 10, 2020
NOT-DK-20-020	Notice of Special Interest (NOSI): Availability of Urgent Competitive Revision Supplements on Coronavirus Disease 2019 (COVID-19) Related to HIV Comorbidities, Coinfections, and Complications within NIDDK’s Mission	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	April 9, 2020
NOT-MD-20-019	Notice of Special Interest (NOSI): Competitive and Administrative Supplements for the Impact of COVID-19 Outbreak on Minority Health and Health Disparities	National Institute on Minority Health and Health Disparities (NIMHD)	April 9, 2020
NOT-TR-20-017	Notice of Special Interest (NOSI) regarding the Availability of Emergency Competitive Revisions to Existing NIH Grants and Cooperative Agreements for Tissue Chips Research on the 2019 Novel Coronavirus	National Center for Advancing Translational Sciences (NCATS)	April 9, 2020
NOT-MH-20-047	Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements and Urgent Competitive Revisions for Mental Health Research on the 2019 Novel Coronavirus	National Institute of Mental Health (NIMH) National Institute of Mental Health (NIMH) National Institute on Aging (NIA) National Institute on Alcohol Abuse and Alcoholism (NIAAA) National Institute on Minority Health and Health Disparities (NIMHD) Division of Program Coordination, Planning and Strategic Initiatives, Office of Disease Prevention (ODP)	April 9, 2020
NOT-TR-20-016	Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements for Tissue Chips Research on the 2019 Novel Coronavirus	National Center for Advancing Translational Sciences (NCATS)	April 9, 2020
NOT-CA-20-043	Notice of Special Interest (NOSI): National Cancer Institute Announcement regarding Availability of Competitive Revision SBIR/STTR Supplements on Coronavirus Disease 2019 (COVID-19)	National Cancer Institute (NCI)	April 9, 2020
NOT-ES-20-015	Notice of Special Interest (NOSI): NIEHS Support for Understanding the Impact of Environmental Exposures on Coronavirus Disease 2019 (COVID-19)	National Institute of Environmental Health Sciences (NIEHS)	April 9, 2020
NOT-DK-20-018	Notice of Special Interest (NOSI): Availability of Urgent Competitive Revision Supplements on Coronavirus Disease 2019 (COVID-19) within the Mission of NIDDK	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	April 9, 2020
NOT-DC-20-004	Notice of Special Interest (NOSI) regarding the Availability of Urgent Competitive Revisions and Administrative Supplements for Research on Coronavirus Disease 2019 (COVID-19)	National Institute on Deafness and Other Communication Disorders (NIDCD)	April 9, 2020
NOT-HL-20-759	NHLBI Announces Availability of Frequently Asked Questions (FAQs) for NOT-HL-20-757, Notice of Special Interest (NOSI): Availability of Administrative Supplements and Revision Supplements on Coronavirus Disease 2019 (COVID-19)	National Heart, Lung, and Blood Institute (NHLBI)	April 8, 2020
NOT-AG-20-022	Notice of Special Interest (NOSI): NIA Availability of Administrative Supplements and Revision Supplements on Coronavirus Disease 2019 (COVID-19)	National Institute on Aging (NIA) National Institute of Mental Health (NIMH)	April 2, 2020
NOT-HG-20-030	Notice of Special Interest (NOSI) regarding the Availability of Urgent Competitive Revisions for Research on the 2019 Novel Coronavirus	National Human Genome Research Institute (NHGRI)	March 31, 2020
NOT-ES-20-014	Notice of Special Interest: NIEHS Worker Training Program Coronavirus and Infectious Disease Response Training (Admin Supp Clinical Trial Not Allowed)	National Institute of Environmental Health Sciences (NIEHS)	March 27, 2020
NOT-TR-20-012	Notice of Special Interest (NOSI): Repurposing Existing Therapeutics to Address the 2019 Novel Coronavirus Disease (COVID-19)	National Center for Advancing Translational Sciences (NCATS)	March 27, 2020
NOT-AI-20-034	Notice of Special Interest (NOSI) regarding the Availability of Emergency Competitive Revisions for Research on Severe Acute Respiratory Syndrome	National Institute of Allergy and Infectious Diseases (NIAID)	March 25, 2020
NOT-AI-20-040	Notice of Early Expiration of “Notice of Special Interest (NOSI) regarding the Availability of Urgent Competitive Revisions for Research on the 2019	National Institute of Allergy and Infectious Diseases (NIAID)	March 25, 2020