Positions
- Professor, Department of Psychiatry, College of Medicine
- Program Director, Center for Addiction Services and Treatment
- Medical Director, Recovery Centers of Arkansas and OASIS Renewal Center
Contacts
- Phone: 501-526-8400
- Fax: 501-526-8499
- E-mail: mjmancino@uams.edu
Research Experience
I have been a project leader on a Centers of Biomedical Research Excellence (COBRE) grant designed to develop a withdrawal paradigm for methamphetamine dependent individuals and currently have an R21 to pilot the efficacy of lisdexamfetamine to alleviate withdrawal and prevent relapse in recently-abstinent methamphetamine dependent patients. I have also collaborated with other investigators as a co-investigator on ongoing and previously conducted research on medication and behavioral treatment approaches for both opioid and psychostimulant dependence.
Research Interests
I am interested in medications development for the treatment of psychostimulant dependence as well as examining improved tapering methods for patient on buprenorphine and the possible transition to naltrexone. Additionally, I have become fascinated with the impact of early childhood trauma and anxiety in opioid dependent persons.
Recent Publications
Tsai PF, Oliveto AH, Landes RD, Mancino MJ. Characteristics of patients
undergoing medication-assisted -treatment for opioid use disorder and their
interest in Tai Chi practice. J Opioid Manag. 2023 Jul-Aug;19(4):329-341. doi:
10.5055/jom.2023.0790. PMID: 37644791.
Thompson RG Jr, Bollinger M, Mancino MJ, Hasin D, Han X, Bush KA, Kilts CD,
James GA. Smartphone intervention to optimize medication-assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial. Trials. 2023 Apr 4;24(1):255. doi: 10.1186/s13063-023-07213-3. PMID: 37016394; PMCID: PMC10071730.
Thompson RG Jr, Bollinger M, Mancino M, Hasin D, Han X, Bush KA, Kilts CD,
James GA. Smartphone intervention to optimize medication assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial. Res Sq [Preprint]. 2023 Feb 15:rs.3.rs-2511936. doi: 10.21203/rs.3.rs-2511936/v1. Update in: Trials. 2023 Apr 4;24(1):255. PMID: 36824884; PMCID: PMC9949224.
Gokarakonda SB, Boydstun JM, Yilanli M, Han X, Kumar N, Oliveto AH, Mancino
MJ. Impact of state and trait anxiety severity on retention and phase
advancement in an outpatient buprenorphine treatment program. Am J Addict. 2022 May;31(3):219-225. doi: 10.1111/ajad.13266. Epub 2022 Mar 3. PMID: 35243715.
Thompson RG Jr, Oliveto A, Thostenson JD, Wilson MP, McGaugh J, Mancino MJ. Utility of a controlled amphetamine withdrawal paradigm among adults who use methamphetamine: A pilot clinical trial. J Psychopharmacol. 2021
Nov;35(11):1420-1430. doi: 10.1177/02698811211050563. Epub 2021 Oct 26. PMID: 34697965; PMCID: PMC10110391.
Coker JL, Ray-Griffith SL, McLeod C, Han X, Mancino M, Kearns GL, Stowe ZN.
Clearance of buprenorphine during pregnancy and neonatal outcomes. Arch Womens Ment Health. 2021 Dec;24(6):933-939. doi: 10.1007/s00737-021-01128-1. Epub 2021 Apr 16. PMID: 33864131.
Phillips SJ, Oliveto A, Mancino MJ, Hendrickson HP. Development and
validation of a rapid liquid chromatography/tandem mass spectrometry method to quantitate gabapentin and buprenorphine in human serum. Rapid Commun Mass Spectrom. 2021 Jul 31;35(14):e9104. doi: 10.1002/rcm.9104. PMID: 33860565; PMCID: PMC8959393.
Kumar N, Mancino MJ, Thostenson JD, McGaugh J, Oliveto AH. Feasibility and
Preliminary Efficacy of Isradipine During Outpatient Buprenorphine Stabilization and Detoxification: A Pilot Randomized, Placebo-Controlled Trial. Subst Abuse. 2020 Nov 23;14:1178221820970926. doi 10.1177/1178221820970926. PMID: 33281447; PMCID: PMC7686602.
Wilson MP, Cucciare MA, Porter A, Chalmers CE, Mullinax S, Mancino M, Oliveto
AH. The utility of a statewide prescription drug-monitoring database vs the
Current Opioid Misuse Measure for identifying drug-aberrant behaviors in
emergency department patients already on opioids. Am J Emerg Med. 2020
Mar;38(3):503-507. doi: 10.1016/j.ajem.2019.05.035. Epub 2019 May 17. PMID:
31221474.