The University of Arkansas for Medical Sciences (UAMS) supports a wide range of shared resources and core facilities designed to advance basic, clinical and translational research. Core facilities are pay-per-use research laboratories or analytical services, which allow investigators access to technologies and services not available in their own laboratories.

A research core facility is a shared resource that provides access to instruments, technologies and services on a pay-per-use basis. Designation as an official UAMS core must be obtained prior to incurring core usage charges.

Brain Imaging Research Center (BIRC) – a Philips Achieva 3 Tesla magnetic
resonance imaging (MRI) scanner, a state-of-the-art research scanner that
addresses focus issues related to human neuroscience. Natalie Morris,
NMorris@uams.edu, (501) 526-8339.

Digital Microscopy Core – operates and maintains computer controlled
microscope workstations ranging from light to electron microscopy. We offer
advice, training and user support for equipment operation (e.g., 3D SIM,
PALM, CLEM, TEM) and sample preparation such as chemical fixation of cell
culture and tissue samples. Jeff Kamykowski – Lab Contact,
JAKamykowski@uams.edu,
(501) 526-7290

DNA Sequencing Core – provides researchers with sequencing data via an
Applied Biosystems Model 3130XL Genetic Analyzer. We regularly achieve read
lengths of 700-900 bases. Allen Gies, GiesAllenJ@uams.edu, (501) 686-6927.

Experimental Pathology (ExPath) Core – provides a variety of
standard pathological stains for histochemical analysis of tissues, including
hematoxylin and eosin, special stains, and immunohistochemistry. Jennifer D.
James, JamesJenniferD@uams.edu, (501) 686-8265.

Flow Cytometry Core – provides multiple physical characteristics of
individual cells in suspension. It can indicate relative cell size and
density or complexity by measuring forward- and side-scattered laser light,
respectively, as well as measure relative fluorescence from biomarker probes
which bind to specific cell-associated molecules. Andrea Harris,
aharris@uams.edu, (501) 686-6927.

Molecular Imaging Core – provides comprehensive services for non-invasive
imaging with a 7 T Magnetic Resonance Imager (MRI) and a MicroPET (Positron
Emission Tomography). Michael Borrelli, MJBorrelli@uams.edu, (501) 526-5897.

Proteomics Core – provides protein characterization by mass spectrometry.
This includes identification of unknown proteins, quantitative comparison of
proteins in biological samples, and mapping of post-translational protein
modifications. Sam Mackintosh, MackintoshSamuelG@uams.edu, (501) 526-6165.

Tissue Biorepository and Procurement Service (TBAPS) – specimen collection
with over 12,000 tissue samples along with de-identified, sample-related
pathology data available from a variety of organs and an extensive list of
diagnoses. We have an IRB approved protocol and general consent form that
allows us to consent patients, acquire samples from the pathology grossing
room, and provide these samples to researchers with appropriate approval.
Remelle Eggerson, EggersonRemelleM@uams.edu, (501) 686-7470.